We are happy to announce the 4th biennial CryoEM 3D Image Analysis Symposium to be held at Granlibakken in March 2022. As in the past, the symposium provides a GRC-like atmosphere with a strong focus on technical aspects of algorithms for image processing in CryoEM. Participants are encouraged to discuss issues in depth, and long discussion sessions are scheduled for each talk. We also have a significant poster-talk session for cutting edge developments and discussion for those bringing new concepts into CryoEM. The meeting has been very well attended in the past with ~150 participants, a large fraction of whom are active methods developers in the field. We have been very successful in attracting a range of people from students and postdocs to senior faculty, and have had very good and in depth discussions on algorithms and methodologies in this field.

It was wonderful seeing everyone in person again! https://www.icloud.com/sharedalbum/#B0q5yeZFhZQcVr

The topics for this year's symposium are:

• Tomography
• Conformational Variability
• Deep Learning in CryoEM/ET
• Improving Maps with Density Modification
• Automation in CryoEM/ET
• Round Tables on Data Compression/Archival/Collection
• Selected Poster Talks